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Publication· 2 min read

Infertility treatment ends with the birth of a baby who has three parents

Spanish doctors: a "three-parent" baby has been born after mitochondrial replacement therapy for the first time — to a 32-year-old Greek woman following 4 failed IVF attempts.

Spanish doctors have made a sensational announcement: for the first time in history, an infertile woman has given birth to a baby conceived through mitochondrial replacement therapy. This means the baby has three biological parents. The mother is a 32-year-old Greek woman who had previously gone through four failed IVF attempts.

Under the technology used, the woman's DNA was placed into a donor egg before being fertilized with sperm. This method is used to treat inherited mitochondrial diseases. Mitochondria are the "power stations" of cells. It is known that a number of hereditary disorders are passed down exclusively through the mother's mitochondrial DNA.

To prevent the disorder from being passed to children, nuclear DNA is extracted from the mother's fertilized cell and inserted into the cell of a third-party donor with healthy mitochondrial genes. This procedure is known as spindle transfer. It results in only 1% of genes being inherited from the third party. On this basis, doctors do not see any moral or ethical concerns and consider the method suitable for treating infertility.

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