A pill blocking the "love hormone" oxytocin may save men from premature ejaculation
Cligosiban, which blocks oxytocin, increases ejaculation time by 3.8 times — tested on 88 men, with expanded trials now in 200 volunteers.
Cligosiban, which blocks oxytocin, increases ejaculation time by 3.8 times — tested on 88 men, with expanded trials now in 200 volunteers.
This is a safe and effective approach. The drug is now being tested by more than 200 men. The medication has also already passed initial trials on 88 volunteers. They took the drug or a placebo on a daily basis. It turned out that at the start of the six-week study, the average ejaculation time was 33 seconds. The duration increased by 3.8 times thanks to taking the drug (this is almost twice as much as in the placebo group).
It is known that the cligosiban being tested is an oxytocin antagonist. That is, it prevents oxytocin from binding to cells in the body. The idea is that if the action of the hormone is blocked, the moment of ejaculation can be delayed. Oxytocin is produced in the hypothalamus, an area of the brain that plays a key role in behaviour. It triggers a mother's attachment to her child, is released during lactation, and underlies empathy, generosity and orgasm.
According to experts, oxytocin levels in men rise during arousal and sexual stimulation. Previously, men with anorgasmia (the inability to achieve orgasm) were successfully treated with an oxytocin nasal spray. Cligosiban, in turn, acts on cells with oxytocin receptors located in the brain and spinal cord, reducing the overall level of the hormone in the blood.
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