Japanese tea recognized as an effective anti-cancer agent
University of Salford: Japanese matcha tea suppresses the mitochondrial metabolism of breast cancer stem cells via the mTOR signaling pathway.
University of Salford: Japanese matcha tea suppresses the mitochondrial metabolism of breast cancer stem cells via the mTOR signaling pathway.
Green tea (matcha) may turn out to be a universal weapon against cancer. Japanese tea makes it possible to keep cancer cells in a dormant state by depriving them of their energy supply. This discovery belongs to the University of Salford.
Scientists examined how matcha affects breast cancer stem cells. It turned out that the tea suppressed mitochondrial metabolic processes (metabolism in the "energy factories" of cancer cells). In this way, cancer cells could not replenish their energy reserves, became inactive, and eventually died.
A more detailed analysis showed that the tea acted on the mTOR signaling pathway, which is important for metabolism in cancer cells. The tea also weakened components of the ribosome (the cellular element that synthesizes most of the proteins essential for cell survival). In theory, matcha may work in the same way as rapamycin. This drug "shuts down" the mTOR pathway.
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