Researchers Identify Two Drugs Capable of Reducing Influenza Mortality
Hudson Institute: gout drug probenecid and arthritis medication AZ11645373 reduce influenza mortality by blocking the P2X7 ATP receptor.
Hudson Institute: gout drug probenecid and arthritis medication AZ11645373 reduce influenza mortality by blocking the P2X7 ATP receptor.
A drug used during World War II as an antidiuretic agent is one of two medications that, according to researchers in Melbourne (Hudson Institute of Medical Research), could reduce the number of people who die from influenza each year.
Probenecid was developed in the 1940s and used to extend the action of penicillin, and is now used to treat gout. The drug has a very good safety profile, which allows it to be used for treating other conditions as well.
The second agent that has attracted the attention of scientists is the arthritis drug AZ11645373. Both agents combat abnormal inflammation — the primary cause of death from influenza infection. They precisely target the P2X7 ATP receptor. This receptor plays a key role in initiating inflammation.
Book a visit — we will pick a convenient time.