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Publication· 1 min read

Scientists explained how to defeat the nagging ringing in the ears

University of Arizona: tinnitus is caused by inflammation in the brain's auditory cortex — blocking the TNF-alpha molecule cleared the ringing in rodents.

Ringing in the ears is an unpleasant disorder that is hard to treat. The University of Arizona has suggested that tinnitus and other deviations linked to hearing loss are caused by inflammation in the part of the brain that processes sound. The problem was solved by blocking a specific protein that intensifies brain inflammation.

Earlier studies showed that hearing loss triggers inflammation in the neural pathway of the brain responsible for hearing. As part of their latest work, American scientists tested how inflammation affects the auditory cortex of the brain using rodents with hearing loss. They also examined the role inflammation plays in the onset of tinnitus.

During the experiment the scientists blocked the TNF-alpha (tumour necrosis factor alpha) molecule, which disrupted the interaction of the neurons essential for hearing. This eliminated the ringing in the ears. Most likely, blocking this molecule will also help to address other related disorders.

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How to overcome ringing in the ears, scientists say